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Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?

Maria Grazia Lampugnani

Author Affiliations

IFOM, FIRC Institute of Molecular Oncology, via Adamello, 16-20139 Milan, Italy

Mario Negri Institute of Pharmacology, via La Masa, 19-20156 Milan, Italy

Journal of Biology 2010, 9:16  doi:10.1186/jbiol232

Published: 8 April 2010


A recent paper in BMC Biology reports that actin stress fibers in adjacent cultured endothelial cells are linked through adherens junctions. This organization might provide a super-cellular network that could enable coordinated signaling and structural responses in endothelia.

See research article webcite