Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?
IFOM, FIRC Institute of Molecular Oncology, via Adamello, 16-20139 Milan, Italy
Mario Negri Institute of Pharmacology, via La Masa, 19-20156 Milan, Italy
Journal of Biology 2010, 9:16 doi:10.1186/jbiol232Published: 8 April 2010
A recent paper in BMC Biology reports that actin stress fibers in adjacent cultured endothelial cells are linked through adherens junctions. This organization might provide a super-cellular network that could enable coordinated signaling and structural responses in endothelia.