The 'stem cell' concept: is it holding us back?
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Journal of Biology 2009, 8:70 doi:10.1186/jbiol177Published: 21 September 2009
Developmental biology, regenerative medicine and cancer biology are increasingly occupied with the molecular characterization of stem cells. Yet recent work adds to a growing body of literature suggesting that 'stemness' cannot be reduced to the molecular features of cell types, and is instead an emergent property of cell lineages under feedback control.