Figure 2.

The conservation of transcription factor production and target gene expression in a given cell type. This cartoon representation shows such conservation of gene expression driven by a lineage-specific arrangement of bound transcription factors (colored ovals). The arrow indicates gene expression. The factors expressed in the ancestral cell can be inferred, but the cis-regulatory arrangement cannot.

Malone and Oliver Journal of Biology 2009 8:32   doi:10.1186/jbiol131
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