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RNA interference in nematodes and the chance that favored Sydney Brenner

Marie-Anne Félix

Author Affiliations

Institut Jacques Monod, CNRS – Universities of Paris 7 and 6, Tour 43, 2 place Jussieu, 75251 Paris cedex 05, France

Journal of Biology 2008, 7:34  doi:10.1186/jbiol97

Published: 13 November 2008


The efficiency of RNA interference varies between different organisms, even among nematodes. A recent report of successful RNA interference in the nematode Panagrolaimus superbus in BMC Molecular Biology has implications for the comparative study of the functional genomics of nematode species, and prompts reflections on the choice of Caenorhabditis elegans as a model organism.