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Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury

Jeannette E Davies1, Christoph Pröschel2, Ningzhe Zhang2, Mark Noble2, Margot Mayer-Pröschel2 and Stephen JA Davies1*

Author Affiliations

1 Department of Neurosurgery, Anschutz Medical Campus, University of Colorado Denver, 12800 East 19th Ave, Aurora, CO 80045, USA

2 Department of Biomedical Genetics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA

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Journal of Biology 2008, 7:24  doi:10.1186/jbiol85

Published: 19 September 2008

Additional files

Additional data file 1:

A figure showing that transplanted GRP cells express neurocan and NG2, but suppress host expression of these molecules at 4 days post transplantation to dorsal column injuries.

Format: EPS Size: 13.8MB Download file

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Additional data file 2:

A figure showing failure of axons to regenerate across GDACNTF-transplanted injuries.

Format: EPS Size: 19.1MB Download file

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Additional data file 3:

A figure showing neuroprotection of injured red nucleus neurons.

Format: EPS Size: 19.8MB Download file

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