Email updates

Keep up to date with the latest news and content from Journal of Biology and BioMed Central.

Highly Accessed Open Badges Minireview

Evolution of virulence in malaria

Bridget Penman and Sunetra Gupta*

Author affiliations

Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, UK

For all author emails, please log on.

Citation and License

Journal of Biology 2008, 7:22  doi:10.1186/jbiol83

Published: 28 August 2008


The pathogenesis of severe malarial disease is not yet fully understood. It is clear that host immunopathology plays a central role, and a recent paper in BMC Evolutionary Biology suggests that the ability of the parasite to stimulate interleukin-10 production is a major factor and speculates on its impact on the coevolution of host and parasite.