Spatially patterned gradients of synaptic connectivity are established early in the developing retina
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Journal of Biology 2008, 7:15 doi:10.1186/jbiol76Published: 9 June 2008
Retinal neurons receive input from other cells via synapses and the position of these synapses on the neurons reflects the retinal regions from which information is received. A new study in Neural Development establishes that the spatial distribution of excitatory synaptic inputs emerges at the onset of synapse formation rather than as a result of changes during neuronal reorganisation.