The future of artemisinins: natural, synthetic or recombinant?
Institut Pasteur, 25-28 rue du Dr Roux, Paris 75724 Cedex 15, France
Journal of Biology 2008, 7:38 doi:10.1186/jbiol101Published: 15 December 2008
Artemisinins are the most important anti-malarial drugs in use today, but are more costly than previous anti-malarials and production and price tend to fluctuate. Alternative ways of producing artemisinins are discussed here in the light of a recent paper in BMC Biotechnology on improving the yield of the precursor, artemisinic acid, in genetically engineered yeast.