Email updates

Keep up to date with the latest news and content from Journal of Biology and BioMed Central.

Highly Accessed Open Badges Minireview

Building bridges with astrocytes for spinal cord repair

Robert H Miller

Author Affiliations

Department of Neurosciences, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-4975, USA

Journal of Biology 2006, 5:6  doi:10.1186/jbiol40

Published: 9 May 2006


Simultaneous suppression of glial scarring and a general enhancement of axonal outgrowth has now been accomplished in an adult rat model of spinal cord transection. Transplantation of a novel astrocyte cell type derived from glial-restricted precursors in vitro raise the eventual possibility of cellular therapy for spinal cord injury.