Email updates

Keep up to date with the latest news and content from Journal of Biology and BioMed Central.

Open Badges Research news

The GTPase switch in ribosomal translocation

Pete Moore

Journal of Biology 2005, 4:7  doi:10.1186/jbiol28

Published: 27 June 2005


Information from careful measurements of the affinity of ribosome-associated proteins for GTP and GDP, and from structural analyses, suggests that elongation factor-G must assume three different structures during protein synthesis and that the ribosome itself acts as a guanine-nucleotide exchange factor. Is it time to re-write the textbook description of translation?