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Intestine in the lung

Jonathan MW Slack

Author Affiliations

Centre for Regenerative Medicine, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK

Journal of Biology 2004, 3:10  doi:10.1186/jbiol8

Published: 8 June 2004


The phenomenon of metaplasia, in which one tissue type is converted into another, is beginning to be explained in molecular terms. The transformation of lung to intestinal tissue has not previously been described, but it is now reported that it can be brought about by prolonged Wnt signaling in late development.