Additional data file 1.

Alignment of the amino acid sequences of Tos3, Pak1 and Elm1 from Saccharomyces cerevisiae, and LKB1 and CaMKKβ (β3 variant) from humans. The alignment was created using PILEUP from the GCG suite [48] and the consensus sequence determined, and color added, using BOXSHADE 3.2.1 [49]. Residues that are identical in at least half of the sequences are colored red, with conservative changes in blue. The consensus sequence is represented by an upper case letter if the residue at a particular position is identical in all sequences, and by a lower case letter if at least half are conserved. Only the conserved central regions containing the kinase domains are shown (the kinase domain of LKB1 is approximately residues 44-309).

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Hawley et al. Journal of Biology 2003 2:28   doi:10.1186/1475-4924-2-28